Sentence examples for molecules are central from inspiring English sources

Conventional T cells expressing clonotypic receptors (TCRs) which recognize peptide fragments of protein antigens complexed with MHC class I (CD8+ cytotoxic T cells) or class II (CD4+ helper T cells) molecules are central players in adaptive immune responses [13], [30].

The small interfering RNA (siRNA) and small hairpin RNA (shRNA) molecules are central to RNA interference.

Small molecules are central to biology, mediating critical phenomena such as metabolism, signal transduction, mating attraction, and chemical defense.

Interactions between proteins and small molecules are central to life-sustaining biochemical processes and the action of many important therapeutic agents.

The human genome encodes 38 VH1-like DSPs (also termed "DUSPs") that function as critical signaling molecules, are central to cell physiology, and are involved in a myriad of pathological processes that lead to disease.

These factors have been extensively studied and several of these key molecules are central players involved in stress responses and cell cell signalling, which are not generally specific to radiation exposure [ 35].

An appreciation of the various mechanisms involved in the numerous physiological pathways affecting the immunoglobulin genes, and hence antibody molecules, is central to an understanding of B-cell development vis-à-vis the generation of immunological diversity.

The insulin molecule is central to metabolic homeostasis, and as such insulin activity is regulated at multiple levels.

A high SNR is most likely a result of the molecule being central in the focal plane rather than at the border of the depth of field.

Integrins are a large family of molecules that are central regulators in multicellular biology.

Our data suggest that miR-155 mediates an important immunosuppressive function in DCs, perhaps through the post-transcriptional knockdown of molecules that are central to T cell activation.