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As given for the embedded SciFinder feature, the matching molecules are accessible via a direct link to the PubChem Index of the identified item.
The phenomenon can be explained by the fact that at the beginning of hydrolysis, the surface molecules are accessible for EG action, and chain ends were sufficient for CBH action.
For the spontaneously formed nuclei at the sample surface, additional molecules are accessible, and the formation of crystallites takes place at the clotrimazole air interface.
The nature of the BBB in regulating which molecules are accessible to the brain, places the system in an ideal position to assist in the uptake and clearance of a-Syn between the ISF and blood.
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By comparison, 50% (12/24) of variant promoter molecules were accessible across the same sites (Fig. 4F) suggesting a slight increase in nucleosome occupancy.
However, in PBMCs from three healthy donors and a carcinoma cell line, all of which express high levels of MLH1, 50%69%% of molecules were accessible across the same sites showing that the slight increase in nucleosome occupancy observed in the variant allele was within the normal range (Fig. 4G).
Although all of the (up to 500) conformers for each molecule are accessible from the PubChem website (http://pubchem.ncbi.nlm.nih.gov), only the first ten "diverse" conformers per compound [11] are available for public bulk download via the PubChem FTP site (ftp://pubchem.ncbi.nlm.nih.gov).nih.gov
Unless otherwise specified, docking sphere with the radius of 30 Å was placed on the OH atom of the Tyr22 residue near the center of the convex side of CT 4. As a result, almost all the surface of the CT molecule was accessible to the ligand binding.
This indicates that some compound molecules are not accessible to the anionic quencher, being intercalated between DNA base pairs.
Fluorescence quenching experiments using external quenchers are also very useful to distinguish between DNA binding modes [9] since intercalated molecules are less accessible to anionic quenchers due to electrostatic repulsion with negatively charged DNA [10].
This suggests that polar heads of DPPC molecules are less accessible than on the two other substrates.
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