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We compared these parent molecules and identified a common basic scaffold, which is included in 32 of 40 clusters and in the search query.
Furthermore, we have found layers with just half the height expected for intact molecules and identified them as broken SMMs which have become decomposed into pre-stages of the molecule.
We conducted a screen for anti-capsular small molecules and identified an agent designated "C7" that blocks the production of K1 and K5 capsules, unrelated polysaccharide types among the Group 2 3 capsules.
They applied this assay in a screen of 2000 bioactive small molecules and identified 46 compounds with anticonvulsant activity.
We changed the initial concentration of each of the molecules and identified the most sensitive parameters of the model.
Using a simple growth-based functional readout, we screened a library of 106,281 small molecules and identified two new inhibitors and three new activators of the mammalian K2P channel K2P2.1 (KCNK2, TREK-1).
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She used magnetic forces, for example, to examine the atomic nucleus in order to study the shapes of molecules and identify compounds.
Checkmol analyses molecules and identifies FGs from a predefined set of 204 functionalities.
The numbering scheme we adopt for this study obeys the IUPAC rules for pteridine like molecules and identifies the atomic positions of all ring nitrogen atoms (potential acceptors) and all the hydrogen atoms (potential donors) that may be involved in hydrogen bonding.
We investigate the important hydrogen bonds and electrostatic interactions between the tudor domains and the peptide molecules and identify the critical residues that stabilize the complexes.
However, using combinatorial techniques, it is possible to rapidly screen a large number of small molecules and identify those that induce a novel phenotype in a cellular or embryonic system [5].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com