Sentence examples for molecule which binds from inspiring English sources

36, 37 Instead of relying on targeting the ATP binding site, this study focuses on designing a molecule which binds to the PBD of Plk1 39, 39 in order to design a specific inhibitor.

The detection relies on a sandwich-type approach using a bioconjugate, where the aminophenyl boronic acid (APBA) served as a recognition molecule which binds with the cell surface glycans and hydrazine (Hyd) served as an electrocatalyst for the reduction of H2O2 which are attached on multi-wall carbon nanotube (MWCNT) (APBA-MWCNT-Hyd).

This molecule, which binds directly to smoothened, is a classical specific inhibitor of the Hh pathway that has been extensively used in in vivo and in vitro experiments.

Jos_I77KQ78K mutates two exposed residues that are close to the active site and are in the interface with the Ub molecule which binds in site 1.

However, C1q is actually not the only multivalent molecule which binds negatively charged moieties.

The first model described a single NF- κB molecule, which binds to I κB α, I κB β and I κB ϵ.

When Fusz et al. [ 22] purified a ribozyme for the aldose reaction in an in vitro selection experiment, they obtained an RNA molecule which bound a bivalent metal, Zn2+.

The regulation that we obtained using an extremely low energy transfer could result from a different synthesis and/or membrane distribution of adhesion molecules, which binds laminin (e.g. integrins).

Currently, two classes of EGFR inhibitors namely monoclonal antibodies (mAbs) and small molecules, which bind to the extracellular ligand-binding domain and the intracellular tyrosine kinase domain of the EGFR, respectively, have been approved for the treatment of cancer patients (Modjtahedi and Essapen, 2009).

It was however difficult as some of the popular knowledge-bases like STITCH, the resource for chemical protein interaction networks (57), did not provide any information on the small molecules which bind the EBOV protein sequences, or those binding other similar proteins.

For example, the helper T cell produces and displays IL-2 receptors on its surface and also secretes IL-2 molecules, which bind to these receptors and stimulate the helper T cell to grow and divide.