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Femtosecond LCLS pulses and their ability to probe specific atoms in a complex molecule were used to resolve a long-standing uncertainty in a benchmark photochemical reaction.
In addition, molecular fingerprints, which characterize the substructure features of a molecule, were used.
Circular RNAs (circRNAs), a kind of covalently closed RNA molecule, were used to be considered a type of by-products of mis-splicing events and were discovered sporadically due to the technological limits in the early years.
A 6 Å of an expanded search grid, a maximum of 20 conformations per fragment, and a maximum of 100 rotatable bonds per molecule were used as general docking parameters.
A random heptapeptide phage display library and monoclonal antibody (MAb) specific to a the P. americana component previously shown to be an allergenic molecule were used to identify the MAb-bound mimotope and its phylogenic distribution.
DMSO only (0.5% v/v) wells, which contained no small molecule, were used as a negative control, while positive controls well consisted of either an FQ WT RNA only or WT RNA as a "small molecule" control.
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This molecule was used to probe relative hydrophobicity of bilayer hydrophobic blocks.
The crystal structure [PDBid: 108d] of a DNA fragment in complex with a TOTO molecule was used as a base to develop our systems.
The drug molecule is used in this coating for two purposes.
Mannose triflate molecule is used as a precursor for synthesis of 18F-FDG by nucleophilic fluorination.
"The default hypothesis should be that this or that molecule is used in coöperation rather than in fighting, because that is what dominates among microbes in the first place," he told me.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com