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A role for PSGL-1 as signaling molecule was indicated by its involvement in activating GTPase Ras and mitogen-activated protein kinases, as well as in inducing the secretion of inflammatory molecules [ 60- 62] or in activating αMβ2 or αLβ2 integrins [ 63- 65].
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ICAM-1 (intercellular adhesion molecule) is indicated as white signal on a black background.
The four peptides in the table in (a) are indicated by arrows and their respective predicted binding affinity for the HLA-A03 molecule is indicated in parenthesis.
The positions of absorbance peaks corresponding to monosome (40S, 60S, and 80S), and polysomes 1 (2-, 3-, 4-ribosomes per mRNA molecule) and polysomes 2 (5-, 6-, 7-ribosomes peRNANA molecule) are indicated.
(15) Our ability to switch these molecules was indicated (predicted) by instabilities in the MDF signal prior to applying the switching field.
Sample and standard molecules are indicated.
Selected viable molecules are indicated by horizontal lines.
The number of water molecules is indicated by the number of H2O.
The binding affinity of dye molecules is indicated by high k L values.
A total of 4638 molecules from a pool of 238,819 molecules were identified as hits while 297 molecules were indicated as highly active.
In this image, scaffolds of bioactive molecules are indicated by magenta background, where the color intensity is proportional to the ratio between bioactive and all molecules containing this scaffold.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com