Sentence examples for molecule that recognizes from inspiring English sources

In order to develop a novel molecule that recognizes a specific structure of RNA, we have attempted to design peptides having l-α-amino acids with a nucleobase at the side chain (nucleobase amino acid (NBA)), expecting that the function of a nucleobase which can specifically recognize a base in RNA is regulated in a peptide conformation.

Taken together, these studies suggest that a small molecule that recognizes structure may be more well suited for targeting highly structured RNAs that require strand invasion by a complementary oligonucleotide.

CD44 is a T cell surface adhesion molecule that recognizes and binds to its ligand hyaluronic acid in tissues and thus enables T cells to migrate into peripheral tissues.

As shown in Fig.  2a and b, the greatest up-regulation of gene expression in the TLR family after inoculation with E. coli was for TLR2 and 4. TLR4 is a transmembrane molecule that recognizes lipopolysaccharides (LPS) produced by gram-negative bacteria [ 76, 77], explaining the need for its up-regulation in response to E. coli.

Hyperthermia may trigger immune responses that inhibit the metastasis of graft tumors [ 30]. "Cluster of differentiation 44" (CD44) is a cell surface adhesion molecule that recognizes hyaluronate and mediates diverse functions, such as cell-cell and cell-matrix adhesion, lymphocyte homing, and T-cell adhesion and activation.

Receptors are protein molecules that recognize and respond to the body's own (endogenous) chemical messengers, such as hormones or neurotransmitters.

In another insight of remarkable power, Dr. Crick in his "adaptor hypothesis," divined that there must exist both a class of carrier molecules that recognize triplets of bases on the messenger and adaptor enzymes that link each kind of amino acid to its appropriate carrier.

The design of molecules that recognize the specific sequence of the DNA double helix or those that can stabilize DNA topoisomerase cleavable complex to stop the progression of DNA process, may be very useful in cancer chemotherapy.

Improvements in laboratory-scale detection of these structures, their clinical diagnosis, and the treatment of disease likely depend on the advent of new molecules that recognize particular states or induce their clearance in vivo.

About 6 years ago, Dana Carroll of the University of Utah in Salt Lake City and colleagues built zinc fingers--molecules that recognize and attach to specific DNA sequences--and joined them with enzymes that slice through the DNA at that same spot to create zinc-finger nucleases.

To investigate specific inhibition of drug-resistant HIV-1 by RNA interference, we designed siRNA molecules that recognize codons 181 188 of the reverse transcriptase (RT) gene of wild-type HIV-1 and HIV-1 carrying the M184V mutation, which confers high-level resistance to the RT inhibitor lamivudine.