Sentence examples for molecule resistant to from inspiring English sources

The chemical structure of the AGs contains an amide bond between the hydrophobic and the hydrophilic moieties (Scheme 1), which renders the molecule resistant to the alkaline conditions, a desirable property in surfactants intended for detergent applications.

The ΔCS mFasL mice express a gene-targeted form of FasL in which the major cleavage sites were mutated to render the molecule resistant to metalloproteinases.

This renders the molecule resistant to degradation.

A single amino acid substitution (ala8→gly) renders the molecule resistant to DPP-4.

The fatty acid side chain also promotes albumin binding that renders the molecule resistant to degradation by DPP-4.

Compared with the other enzymatic mechanisms of contrast formation, fibrin polymerization and a cross-linking mechanism that localizes and makes the molecule resistant to degradation would generate a stronger and more persistent contrast.

Consequently, ceragenins are novel molecules resistant to proteolysis and promise opportunities in treatment of bacterial, fungal, and even viral infections.

Then, the percentage of methylated molecules was estimated as the proportion of DNA molecules resistant to digestion in the SacII-treated aliquot, evaluated by quantitative PCR in a LightCycler 480 System (Roche), with primers P28 and P29 (see Additional file 1: Table S1), and using the SacII-untreated aliquot as reference.

They also go on to suggest that extracellular ribonucleases are very stable molecules, resistant to proteolytic degradation, thereby providing a rigid scaffold ideal for evolving an effector arsenal, in which exposed loop regions subjected to positive selection allow diversification and evasion of host recognition.

It has been observed that cellular proteins that are strongly associated with the DSS1 molecule are resistant to SDS treatment or denaturation.

These include prolonged induction of the mitogen-activated protein (MAP) kinase Erk1/2 leading to enhanced expression of the activator protein-1 (AP-1) transcription factor, c-Fos [ 28]. c-Fos is essential for osteoclast generation [ 29], and mice deleted of the molecule are resistant to the bone loss of inflammatory arthritis.