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Our studies suggest that utilization of a combinatorial strategy to alter H-bonding capacity across a simple carbohydrate molecule may represent a novel drug design strategy.
Among new therapeutic approaches, osteoprotegerin (OPG), an anti-bone resorption molecule may represent a promising candidate to inhibit RANKL-mediated osteolytic component of ES and consequently to limit the tumor development.
This is the first demonstration of a functional role for plakoglobin/γ-catenin in the metastatic process, indicating that this molecule may represent a target for antimetastatic therapies.
Although the role of polyP and its potential in antithrombotic therapy remain largely unclear, the general consensus is that this previously under-appreciated inorganic molecule may represent an important player in the thrombotic haemostatic environment [7].
The presence of the soluble fragment of this molecule may represent either an adaptive excess of the protective molecule on an essentially healthy endothelium, or be a marker of excessive endothelial damage if also accompanied by high levels of other markers such sICAM (Wu et al., 2003).
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These small molecules may represent new classes of ER antagonists, and may have the potential to provide an alternative for the current anti-estrogen therapy.
These results indicated that the tetrahydro-triazolopyrazine motif of the molecules may represent a novel scaffold for the development of hsp90 inhibitors.
A significant lowered level of adhesion molecules may represent a lower risk of the development of endothelial dysfunction and formation of atherosclerotic plaque.
This feature is consistent with the understanding that the biochar-surface atomic layer accessible to the ozone molecules may represent only a very small fraction of the total biochar mass.
In light of the restricted fashion by which these ligands are primarily confined to tumors, these molecules may represent an excellent target for cancer therapy.
Also antiangiogenetic molecules may represent a valuable option [ 72].
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com