In order to study membrane fusion, the researchers needed a means of binding the virus onto their synthetic membranes — and unlike flu and other viruses, no one knew which receptor molecules were key for Zika to enter a cell.
The potency, physicochemical properties, and stability of the drug molecules are key parameters for designing the most suitable drug delivery system.
MDR1 efflux is dependent on specific structural features of the transported molecule, a key requirement for the application of the SALI/SCI approach.
In addition, expression of caspase-1 (Casp1), a downstream effector molecule and key enzyme for IL-1β production (Black et al. 1988), exhibited a similar pattern to Tlr4 expression.
The immobilization of aptamer and the introduction of signal molecule are two keys for the development of electrochemiluminescence (ECL) aptasensor.
The flight also changed the expression of 167 of the bacterium's genes, including one for a protein called Hfq, which could be the key molecule responsible for the increased virulence.
Although the exact role of CD81 in the course of virus infection is not well defined, it is a key molecule required for productive infection by HCVpp and HCVcc of Huh-7 cells [3], [4], [5], [6], [7], [10], [32].
The key molecule required for water retention within skin is HA.
The extracellular signal-regulated kinase, ERK, a subfamily member of MAPKs, is a key molecule responsible for survival under hypoxia [ 6, 7].
Recombinant Phl p 5 is a key molecule used for diagnosis of grass pollen allergy 35, and it is incorporated as a component of new vaccines developed for specific immunotherapy of grass pollen allergy 36.
The modified motifs encompass the internal and the C-terminal (loss of the MTTV sequence) Dvl binding domain, and hence, Dact4 proteins may be unable to regulate this key molecule essential for all Wnt pathways.
