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The counts in the fingerprint then represent how often this substructure is found in the molecule it represents.
One Rmap is the restriction map of a single genomic DNA molecule; it represents the most fundamental unit of map data in functional ways akin to a sequence read.
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The approach relies on the concept of scaffolds described in section "Scaffold based approaches": the elements constituting the molecule cloud are the scaffolds obtained from a set of molecules, whereas each scaffold is scaled according to the number of molecules it represents.
Our finding raises the question whether miR1120 is a true miRNA molecule or it represents a small noncoding RNA such as a siRNA, especially considering its size of 24 nucleotides.
Hence, in the new meta-GRN model, each component is identified by its node's identity (i.e., the gene or molecule that it represents) and the spatial location where it is found, which is distinguished by the initial letter of the attractor expected there.
Herceptin has boosted the interest of clinicians in immunotherapy based on this molecule as it represents the first mAb approved for therapeutic use with proved survival benefit in patients with HER-2-positive breast cancer with metastasis (Baselga et al, 1996; Slamon et al, 2001).
The idea consists of treating each particle as a sample drawn from the pool of molecules that it represents; this way, the actual location of a tracked particle is seen as a sample drawn from the density function of the location of molecules represented by that given particle, rigorously represented by a kernel density function.
Among calcium-channel blockers, flunarizine was chosen as, according to guidelines, it represents the molecule with the highest level of evidence of efficacy [35 37].
Thus, it represents a molecule whose loss may lead to the disruption of multiple signaling cascades involved in tumorigenesis.
It corresponds to the collective velocity of an enormous number of real molecules that the simulated molecule represents.
Target molecule: represents the molecule target of the interaction.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com