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Remarkably, even a single DT molecule is sufficient to kill a eukaryotic cell [ 23].
The large numbers of short reads produced by next-generation sequencers provide opportunities for development of new applications where sequencing only a portion of a molecule is sufficient.
These data provide evidence for high processivity of PcrA in plasmid unwinding: one PcrA molecule is sufficient to unwind one plasmid without premature dissociation.
Here our results suggest that a stretch of 30 50 nt of high similarity inside the dsRNA molecule is sufficient to observe an efficient RNAi.
Apparently, the strength of specific solid-state effects is weak, and a simple comparison between the solution and solid-state resonances, and the simple calculation for the isolated molecule is sufficient for structural analysis.
However, surface binding with one of the five available antigen-binding sites of an anti-CII IgM molecule is sufficient for complement fixation, and neutrophil binding via Fc receptor and/or C3 receptor can take place.
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"Neuritin produced a response that looked exactly like an antidepressant," says Duman. "I was surprised to find this molecule was sufficient, by itself, to block the effects of stress and depression".
This induction of RANKL and downregulation of OPG in myeloma cell-BMSC co-cultures is abrogated by neutralizing antibody to α4 integrin receptor subunit, and treatment of myeloma tumor cells with a recombinant soluble form of vascular cell adhesion molecule (VCAM -1 (a ligand for the α4 adhesion molecule) was sufficient to induce RANKL expression [ 5].
In the case of Si{110}, significant reduction in the etch rate indicates that the layer of adsorbed surfactant molecules is sufficient enough to shield the surface from the etchant.
In the mouse model of myositis, the forced expression of MHC class I molecules is sufficient to precipitate the onset of myositis in mice.
Therefore, a reduced model structure that neglects all receptor states with two bound insulin molecules is sufficient at low insulin concentrations.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com