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Unless the therapeutic molecule is designed to be allele-specific, both wild-type and mutant protein will be suppressed by an RNA interference treatment.
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A new self-assembling molecule was designed and synthesized.
The molecule was designed to have push pull structure and was synthesized by Knovenagel condensation reaction.
The molecule was designed with azole, thiol functional groups and carboxylate tail group.
To facilitate intracellular delivery of hydrophilic drugs, a general lipophilic carrier molecule was designed and synthesized.
A novel surfactant molecule was designed through an economic processing technique.
That is, the molecule being designed may also bind to the equivalent binding site in the closely related protein target, and this may lead to undesirable consequences.
However, the straight-chain molecule was designed with a "swing" structure, which made the transfer of electrons possible.
A synthesis of this molecule was designed and carried out to produce sufficient material for further testing.
In order to progress the study on both MRI and BNCT, the novel compounds containing 19F and 10B atoms in a single molecule were designed and synthesized.
In order to develop practical tools for BNCT and MRI, novel compounds containing both the trifluoromethyl group and 10B atom in a single molecule were designed.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com