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Detecting protein-small molecule interactions using fluorous small-molecule microarrays.
Two assays are presented to exemplify the detection of small molecule interactions with the biosensor.
This study provides insights relating to the interaction network nature of allostery in complex DNA small molecule interactions.
A wide range of applications is foreseen for this system in the development of biochips, high sensitivity biosensors and the detection of single molecules and single molecule interactions.
Collectively, our studies illustrate the power of chemical proteomics to profile protein-small molecule interactions of lipid kinases for fragment-based lead discovery.
The results demonstrated that the rupture force of this single bond was 15 pN, which was significantly smaller than those of other known molecule interactions to date.
Similar(17)
In the storage of molecular hydrogen, surface-molecule interactions are responsible for the storage properties of the materials.
The molecule-zeolite interactions determine the orders of magnitude of the diffusivity, whereas the molecule-molecule interactions could alter the concentration dependence of a diffusivity.
Since the shift in λmax values with solvent type reflects dye-molecule interactions, an attempt was made to study this phenomenon in detail.
The carbon dioxide molecule was predicted to bind only weakly to nanotubes, and the tube-molecule interactions can be identified as physisorption.
Drug-molecule interactions can be queried at the second level.
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