Sentence examples for molecule in cell from inspiring English sources

WT TTR was observed to interact with all the A-Beta forms tested (soluble, oligomers and fibrils), with similar strengths and was able to inhibit the aggregation and disrupt preformed A-Beta fibrils, behaving as well as a protective molecule in cell culture through inhibition of apoptosis [19].

Finally, C-6 analogs were designed to explore the functional group tolerance of the molecule in cell viability assays.

Taken together, the data clearly indicate that it is PI5P, and not PI 4,5 P2 produced from PI5P, that is the crucial signaling molecule in cell migration.

We and others have demonstrated that BIM, a BH3-only pro-apoptotic BCL-2 family protein, is a critical molecule in cell death induced by GCs treatment.

These tumors consisted predominantly of undifferentiated basal cells, which were amplified in response to β-catenin activation, thereby implicating this molecule in cell fate decisions in the mammary gland [ 52].

This was attributed to an indirect effect of inhibiting nuclear export of paxillin, a protein best known for its role as a signaling adaptor molecule in cell adhesion complexes.

We propose that these exceptional physical characteristics enable a rapid and specific transport mechanism in the physiological context, a notion supported by single molecule in-cell assays on intact NPCs.

Ribosomal RNA (rRNA), molecule in cells that forms part of the protein-synthesizing organelle known as a ribosome and that is exported to the cytoplasm to help translate the information in messenger RNA (mRNA) into protein.

It is required for proper proliferation and function of NK cells, T cells, B cells, macrophage and dendritic cells and is an important effector molecule in cell-mediated killing of certain tumours.

AMPK is an important nutrient-sensing molecule in cells and is a negative regulator of insulin-stimulated signaling pathways.

Xie P. TRAF molecules in cell signaling and in human diseases.