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Recent evidence suggests that the expression of Fas, a molecule implicated in the initiation of apoptosis in various cell types, is increased at sites of atherosclerotic plaques.
These findings demonstrate that Ebf2 is a new molecule implicated in peripheral nerve development and a potential candidate gene for peripheral nerve disorders.
In this context, pituitary adenylate cyclase-activating polypeptide (PACAP) has over the past decade emerged as a key signaling molecule implicated in migraine [2] and possibly also in cluster headache [3].
Cadherin-11 (Cad-11, also known as OB cadherin or CDH11) is a cell-to-cell adhesion molecule implicated in many biological functions, including tissue morphogenesis and architecture, extracellular matrix-mediated tissue remodeling, cytoskeletal organization, epithelial-to-mesenchymal transition, and cellular migration.
We investigated whether the metacyclic trypomastigote stage-specific surface molecule gp82, a Ca2+-signal-inducing molecule implicated in host cell invasion, displayed the ability to induce actin cytoskeleton disruption, using a recombinant protein (J18) containing the full-length gp82 sequence fused to GST.
These factors are recruited by RNA, the single-stranded molecule implicated in numerous cellular processes, from coding and decoding genes to protein synthesis.
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In contrast to past trial-and-error discovery, we are starting to see designer drugs that target known sites on molecules implicated in disease.
α-Neurexins are essential synaptic adhesion molecules implicated in autism spectrum disorder and schizophrenia.
Angiopoietin-1 (Ang-1) and -2 (Ang-2) are molecules implicated in angiogenesis and regulation of endothelial permeability.
Polyamines are ubiquitous molecules implicated in plant growth and development, and in the establishment of plant microbe interactions.
The definition of immunodominant peptides derived from RhD and Jka BGAs, the cytokine patterns induced and the HLA class II molecules implicated in their presentation are analyzed.
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