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DRD4 encodes a receptor molecule for a neurotransmitter called dopamine.
In some cases the carbohydrate groups are necessary for the stability or activity of the protein or for targeting the molecule for a specific destination.
These results provide important information to design a new enediyne molecule for a DNA target.
Figure 4 Spectral functions of the molecule for ( a ) V = 0.0 eV and (b to e) V = 0.1 eV.
The concept was demonstrated using the drugs camptothecin, which has a hydroxy functional group, and tryptophan, which is a model molecule for a drug with amine functionality.
The Neighbor Preference Index (NPI) of a molecule for a given data set was introduced, which quantified whether a molecule had more 2-D or 3-D neighbors in the data set.
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These lectins were conjugated with fluoro-microbeads and used as a detection molecule for an antibody lectin sandwich assay.
SE quantifies the susceptibility of a molecule for an electrophilic attack.
The SE has been designed to quantify the susceptibility of a molecule for an electrophilic attack (Tehan et al., 2002b).
Statistically significant correlations have been demonstrated between carcinogenic activity, toxicity and number of carbons per molecule for an extensive set of nitrosamines.
CD44 is an important adhesion molecule for hyaluronan, a major component of the extracellular matrix (ECM).
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