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A SECRETED signalling molecule encoded by the Wnt-1 gene is required for development of the central nervous system.
These analyses indicated that seven of the mAbs (PG77A, PG96A, PG167A, PGB78A, 3C/9, MIL13, NHT 101) recognized the portion of the CD45 molecule encoded by the A exon (CD45RA), while one (MIL15) was specific for that portion encoded by the C exon (CD45RC).
The beta-2 domain of the conserved HLA-DR alpha molecule encoded by the HLA-DRA1 locus interacts with the CD4 molecule in human lymphocytes [19].
To this end, we have developed a system that maintains the divergent biosynthetic pathways of the antibody and adenovirus components via use of a secreted scFv molecule encoded by the vector.
This would parallel previous reasoning suggesting that in human PAM specific P. falciparum variants, such as the variant expressing the PfEMP1 molecule encoded by the var gene var2csa, are expanded via the increased cytoadherence of the iRBC to the placental receptors, prominently the CSA [39].
In adult tissues, TBB3 is mainly expressed in the brain and PNS and used as a neuron-specific marker molecule encoded by a gene located at the long arm of chromosome 16 in man [41] thereby highlighting a possible pathogenic role between such autoimmune response and the occurrence of CM.
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There are two classes of MHC antigens: class I molecules, encoded by three genes, and class II molecules, encoded by four possible sets of genes.
You can tell that's the case because as soon as someone mentions gene products, the myriad protein molecules encoded by genes, suddenly there's a switch-off.
This cell-surface protein is the product of one of a group of molecules encoded by the genes of the major histocompatibility complex (MHC).
Molecules encoded by these genes are responsible for the presentation of peptides to the T-cell receptor of CD8+ lineage T cells10,35.
Successful pathogens use effector molecules, encoded by Avr genes, not only to suppress host immunity but also to manipulate host cellular mechanisms for their own benefit, leading to effector-triggered susceptibility (ETS 28.
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