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The presence of the kinetic barrier due to the large potential difference between donor and acceptor molecule decrease the feasibility of this reaction (Saha et al. 2010).
The study showed that the increase of length of substituent at R2 position and the increase of dipole moment of the molecule decrease the anticancer activity of these compounds, presence of bromine atom at R3 position and hydrophilic substitution at R2 position are advantageous to the activity.
Like butanol in dextran sulphate solutions, therefore, collagen accumulates into the enriched HDW in the double layer; the many hydrophobic patches along the molecule decrease the dielectric constant and thin the double layer.
A comparison of the X-ray crystal structures of the guest-free and polyether- and tert-butyl alcohol-inclusion compounds indicates that the enclathrated polyether or tert-butyl alcohol molecule decrease the π-stacking between hosts and enlarge the distance between the host host aromatic planes.
Conversely, modifications of the disordered N-terminal portion of PACAP molecule decrease the biological activity of the peptide (Onoue et al., 2001; Bourgault et al., 2009b).
If levels of this putative signaling molecule decrease, the cell imports more iron from the cytosol into mitochondria, resulting in mitochondrial iron overload and cytosolic iron deficiency, which slows cytosolic Fe−S cluster biogenesis.
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In this case, the increase of the length of carbon backbone chain in a molecule decreases the limiting wetting angles.
It is based on the assumption that the adsorbed molecule decreases the surface area available for the corrosion reactions to occur.
Replacement of a methylene group by an oxygen atom in the spacer segment of the molecule decreased the thermal stability of the mesophase.
The relationship between E q, V G ) and V G is non-linear because the atoms closest to the dielectric region screen V G for the rest of the molecule, decreasing the gate coupling.
substitution of the amino acid B28 proline by lysine and B29 lysine by proline in the B chain of the insulin molecule decreases the tendency of the molecule to associate to form hexamers, resulting in an increased absorption rate from subcutaneous injection sites.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com