Sentence examples for molecule coordinated by from inspiring English sources

In ColE9, it has been proposed that the water molecule coordinated by the metal ion and His131 acts as the general acid that protonates the leaving group [29].

The active site of CA contains a Zn2+ molecule coordinated by three histidine ligands, His94, His96, and His119, and a solvent molecule.

Structural comparison revealed that all closed structures share a tightly bound "catalytic water" molecule coordinated by two conserved glutamine residues (Gln262 and 266 in PTP1B).

This is not surprising from a structural point of view, since the γ-phosphate binding pocket is quite small and only contains two water auxiliary molecules outside of the axial water molecule coordinated by the vanadate anion.

The D64, K63 and a water molecule coordinated by R138 from PTPN18 composed five backbone H-bonds of the HER2 pY peptide and positioned the peptide along specific PTPN18 surface loops, which were the phosphotyrosine recognition loop, the P-loop, the WPD loop, the Q loop and the α-1 helix from N- to the C-terminus.

Namely, the ANTXR2-bound divalent cation is directly coordinated by a carboxylate-containing side chain (residue D683) of PA as well as by the MIDAS threonine and serine residues, and water molecules coordinated by the MIDAS aspartate residues (Fig. 1) [8], [8].

The trigonal planar AlF3 molecule is coordinated by an ADP β-phosphate oxygen, as predicted for AlF3 mimicking the transition state of an in-line attack on the Ser/Thr residue of the substrate (Madhusudan et al., 2002), and the lower conformation of the glycine-rich loop is well defined.

This water molecule is coordinated by three invariant active-site side chains [E710, N845, and Q849 in Pol I KF)] and interacts with the minor groove of the nascent base pair; its absence could potentially affect nucleotide binding in the complexes that play a role in the early fidelity checkpoints.

The results revealed that the iron atom is coordinated by TPP molecules at Fe/Si system.

The first water molecule is tightly coordinated by the C-terminal carboxylate and the phenolic hydroxyl groups of Tyr147 and Tyr159 while a second water molecule bridges the piperazine group and the carboxylate.

The resolution is 2.3 Å and density shown is from a 2Fo Fc electron density map contoured at 1σ. DOI: http://dx.doi.org/10.7554/eLife.03604.013 N3 of the uracil base interacts with both Thr 155 and Glu 156 through a single water molecule that is coordinated by both residues.