Sentence examples for molecule compounds and from inspiring English sources

In addition, his lab has developed methods for the systematic discovery of small molecule compounds and combinations that can inactivate master regulator proteins in cancer, thus providing novel therapeutic hypotheses that can be validated pre-clinically and clinically.

Dr Banks has extensive experience in planning, conducting, and analyzing Phase 1 through 3 clinical studies as well as cross-functional experience in strategic planning and execution of entire drug development programs with both small molecule compounds and biologics.

Fu et al. noted the emergence of spontaneously beating cells during iPSC reprogramming using a cocktail of small molecule compounds and developed a two-step reprogramming process to induce and stabilize iCM reprogramming (Fu et al., 2015).

Therefore, to better understand how our GCS inhibitors are affecting glucose metabolism in different tissues, we have performed hyperinsulinemic-euglycemic clamps in diet-induced obese (DIO) mice that had been treated with our small molecule compounds, and used radio-labeled metabolites to determine the effect of drug treatment on the uptake of glucose into different tissues.

Connectivity mapping integrates gene expression profiling with advanced algorithms to connect genes, diseases and small molecule compounds and has been applied in a large number of studies to identify potential drugs, particularly to facilitate drug repurposing.

The forecast studies focus on the isolation and culture of stem cells from dermis, and the differentiation ability of the stem cells was found, which can differentiate into adipocytes, osteoblasts, chondrocytes, and neurocytes under the induction of small molecule compounds and the induced factors.

Drawing upon the extensive experiences of our staff in the fields of target and molecular discovery, the Center offers access to small molecule compound and siRNA collections as well as expertise and instrumentation for high throughput assay design and execution.

Plants can be used to produce a diverse repertoire of complex small-molecule compounds and recombinant proteins that are valuable as industrial and pharmaceutical products.

Using this assay we screened a library of 56,000 diverse small-molecule compounds and identified several chemical structural families that inhibit Bmi1/Ring1A ubiquitination activity.

However, how small-molecule compounds and external stimuli like low pH activate and integrate intracellular signal transduction pathways to form completely new regulatory networks is still largely unknown.

A stronger case would be made if the authors tested whether their small molecule compounds bind to and reduce toxicity of oligomers.