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Such buffering bioadhesive formulations include ACIDFORM [ 42, 43] based on small molecule components, and preferably polymers with built-in acidic buffering capacity: Carbomer 974P (BufferGel) [ 44] and CAP (Fig. 2, 3, 4, 5; Table 1).
Moreover, activated charcoal decolorized the 7H9 medium (see Fig. S1a in the supplemental material), suggesting that it bound small molecule components, and the charcoal quenched the fluorescence of resazurin (see Fig. S1b in the supplemental material), whose reduction to resorufin is a useful quantitative reflection of relative mycobacterial numbers (30, 31).
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The basic entities of the language are molecules (components) and sub-cellular locations (compartments).
The UV-absorbing and fluorescent emission properties of these polymers were investigated and compared to those of the corresponding single structural π-molecule component and H-type stacking polymer (H-3).
Network-free simulation is a particle-based, or agent-based, approach that involves tracking individual molecules and molecular components; the cost of simulation depends on the number of molecules, molecular components, and rules considered but not the number of chemical species or reactions implied by rules [ 40, 41].
To represent different molecule component states and binding site statuses Simmune uses the icons listed in Figure 1.
Since complexes of the same species are merely different in the molecule component states and binding site statuses we can, instead, present only the complex species within the network overview, and provide complex- and reaction-specific information upon user request.
PLC γ1 can only bind to EGFR when both molecule component states "bndPLCg992" and "bndPLCg1173" are "off".
To accommodate these constraints in our model, we assigned two molecule component states "bndPLCg992" and "bndPLCg1173" to the EGFR species indicating whether a PLC γ1 is bound to either one of the two binding sites pY992 and pY1173, respectively.
The molecule component describes the protein and small molecule information, e.g., p53 protein and Mdm2 protein.
Figure 10 shows the representation of complex species EGFR with the aforementioned binding sites and molecule component statuses.
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