De-activation involves the GAP proteins helping the Rab GTPase to hydrolyse a bound GTP molecule, which leaves a GDP molecule bound to the Rab.
The heme ring consists of a porphyrin molecule bound to an iron (Fe) atom.
The efflux mechanism is a molecule bound to a bacterium's outer membrane.
Transported microtubules bound to cy5-labeled surface-immobilized microtubules would start sliding until encountering a NeutrAvidin molecule bound to a biotinylated surface-immobilized microtubule.
In contrast, a maximum of one soluble CD4 molecule bound to functional SIV trimers with a truncated a gp41 tail.
SYG-1, a synaptic adhesion molecule, bound to SKR-1 and inhibited assembly of the SCF complex, thereby protecting nearby synapses.
An X-ray crystal structure of enzymatically most potent molecule bound to LDHA revealed two additional interactions associated with enhanced biochemical potency.
An X-ray co-crystal structure of a representative molecule bound to KDM5A showed that these inhibitors are competitive with the co-substrate (2-oxoglutarate or 2-OG).
An alternative to simple electron transfer is the transfer of a hydrogen atom from a water molecule bound to chromium II) to the hydroxide ion (OH−) bound to iron III).
However, the azithromycin molecule bound to MphH is positioned ~3 Å closer to the nucleotide binding region as compared to its position in either the MphA or MphB active sites (Supplementary Fig. 7a).
Specifically, we explore application of the Fukui function, the global hardness and softness, the local softness, and the dual descriptor to pure metallic and core shell nanoparticles, with and without a CO molecule bound to the surface.
