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BH3-only proteins are low abundance proteins and of small molecular weight, therefore making them difficult to detect by mass spectrometry.
Notice that this technique does not permit to detect the downregulation of VRK2 expression levels since it separates the proteins by their molecular weight, therefore what is detected is the redistribution of the initial protein present in whole cell extracts (Fig. 9A) in each individual fraction corresponding to a different molecular size.
Thiomers are not absorbed from the GIT due to their high molecular weight; therefore systemic side effects are eliminated and their use as pharmaceutical excipients for their P-gp inhibitory properties is greatly beneficial [ 72].
PAHs are serious pollutants and health hazards, and they occur as complex mixtures, including low and high molecular weight; therefore, degradation of PAHs in the environment is becoming more necessary and interesting.
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This is probably because of the presence of gluten proteins from different loci but having the same molecular weights, therefore becoming visible only as one gluten protein band.
Plants do not typically produce high molecular weight dsRNA, therefore the presence of dsRNA makes it an attractive target for plant virus diagnostics.
In addition to these promising findings, it is important to point out that no calcium was added, and that bis-amine has a lower molecular weight, and therefore is less shear-sensitive than the commercial high molecular weight polymers used to treat MFTs in commercial applications.
The gel filtration analysis does not have enough resolution at its high molecular weight boundary, therefore, we employed sucrose density gradient centrifugation (SDGC) to confirm this observation.
Although possessing smaller molecular weight and therefore faster metabolism as well as tumor uptake than the whole antibody, the Fab single fragment has a lower binding affinity than the whole antibody, as we have seen for 125I-hFab-Met-1 125I-hFab-Met-1 125I-hFab-Met-1 125I-hFab-Met-1s lobtainedn 125I-Met5 (~13%EIA).
It is worth noting that much of the material within the human CD1d ligand pool that we were not able to identify appeared to be of relatively high molecular weight, and therefore it is possible that more glycosylated ligands are present, and that these may include GPIs.
Proanthocyanidins are polymers of high molecular weight, and therefore oligomers larger than trimers are unlikely to be absorbed in the small intestine in their native form [ 19].
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