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The selectivity profile of these new, low molecular weight structures may guide the design of specific, non-peptidic inhibitors of binuclear aminopeptidases.
NMR techniques for screening aimed at the discovery of novel ligands or low molecular weight structures for fragment-based build up procedures are being applied commonly in the industry.
Therefore, we have concluded that CD95 deglycosylation does not influence formation of these CD95 high molecular weight structures.
An extension of the incubation time to 1.5 h resulted in a reduction of dimers and trimers and the appearance of high molecular weight structures.
The evolution of these high molecular weight structures is likely linked with their extracellular occurrence to avoid elimination from the extracellular fluid by excretory processes.
They can recognize a broad range of targets ranging from small molecules, such as ions, vitamins, antibiotics, to high molecular weight structures, including enzymes and antibodies.
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Molecular weight, structure, morphology, and thermal properties were characterized.
The resulting brominated polybutadiene-polystyrene (BrPBPS) polymeric flame retardant contains similar aliphatic bromine as in HBCD but with a higher molecular weight structure.
Several studies dealt with relationship between polymer molecular weight, structure or architecture and properties, but only recently, researchers are trying to develop tools for creating fully monodisperse macromolecules or even sequence-defined ones.
This might be due to its relatively low molecular weight structure [9].
The amide product could be easily separated from the ester formed as a minor product (Scheme 1) inspite of similarity in molecular weight, structure and adsorption properties.
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