Polystyrene (PS) chains with molecular weights comprised between 15,000 and 60,000 g/mol and narrow polydispersities were successfully grown from the surface of silica nanoparticles by nitroxide-mediated polymerization (NMP).
In this study, the encapsulated triclosan in the low molecular weight PLLA comprising 30% triclosan (LATC30), mixed with nano hydroxyapatite (nHA) are dispersed in PLLA of larger molecular weight via melt blending.
To assess the potential use of the cytoplasm-to-nucleus translocation of PIR in high-throughput, microscopy-based screening for novel proteasome inhibitors, we tested 1,992 low molecular weight compounds comprising the NCI Diversity Set chemical library.
The presence of lower molecular weight species comprising the C-terminal region of TAR DNA-binding protein 43 (TDP-43) is a characteristic of TDP-43 proteinopathy in amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD).
The mass accuracy for such molecular weight was comprised between 0.1 and 0.2%.
Tc toxins are large molecular weight toxins comprised of three protein subunits: A, B, and C. For each subunit, there are multiple genes that can encode a similar function (e.g. xptA2 and tccA2 both encode A subunit proteins) [ 88, 89].
These proteins are grouped into high molecular weight protein families, comprising the HSP100, HSP90, HSP70/DnaK and HSP60/GroE, and low molecular weight families, including Heat Shock Protein 20 (HSP20) or small heat shock proteins (sHSPs) of 15 42 kDa [ 12].
TDP-43 proteinopathy is the hallmark of the majority of ALS-FTLD cases, and biochemical characterization of pathological TDP-43 from disease tissues indicates that abnormal lower molecular weight TDP-43 species comprising the C-terminal region may play a role in disease pathogenesis [ 16].
In addition the bridging residues in branched polymers arising from use of an unsaturated crosslinking comonomer have been chemically cleaved to yield the linear oligomers of much narrower molecular weight distribution that comprise the branched structure.
The low-molecular-weight antioxidants comprise a concerted system of water- and lipid-soluble molecules like glutathione (GSH), ascorbic acid, histidine-related compounds (carnosine, homocarnosine, and anserine), melatonin, uric acid, lipoic acid, and tocopherols [ 59].
