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For the non-CNS oral drugs, the most populated molecular volume range was from 1000 to 1200 Å.
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The triclinic modification, with respect to the monoclinic one, presents the advantage of higher uptake of pollutants having molecular volume in the range 0.13 0.22 nmainlyinly when present only as traces in water or in air.
The δ-clathrate forms of syndiotactic polystyrene (s-PS) containing a homologous series of guests characterized by an increasing molecular volume (n-alkanes ranging from n-pentane to n-dodecane) have been investigated.
The TP-computed molecular volume showed the most populated range was from 800 to 1000 Å for the CNS drugs.
It has also been shown by us [ 25] and by others [ 24] that there is a close correspondence between the measured and predicted molecular volumes for various proteins over a wide range of molecular masses; hence, molecular volume is measured reasonably accurately by AFM imaging.
However, when a constant ST thresh value is used across a range of volumes, each increase in the molecular volume may result in a very rapid growth of the shape space, and hence, the number of reference shapes per volume.
[Note that the ST thresh is the "maximum" ST value between clusters since the ST score is a similarity measure, not a dissimilarity measure.] If the clustering is performed using the same ST thresh value for a volume range, the shape diversity as a function of each molecular volume size may be evaluated by the growth of the number of reference shapes.
We have shown that by comparing a range of solvent vapors (water and C1 C4 alcohols), the magnitude of the effect correlates to the molecular volume of the solvent molecule.
● Tephra fall volume (range).
● Bulk volume (range).
● DRE volume (range).
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