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P. aeruginosa isolates underwent molecular (Variable Number Tandem Repeat) and phenotypic characterisation (Table 1).
A variable assortment of different genes (or other molecular variable) can be used to issue simultaneously several different prognostic or predictive results.
Microsatellite instability (MSI) is a molecular variable with prognostic value that has previously been associated with EGFR and PTGS2 expressions in primary CRC and, as such, qualifies as a potential confounding factor (Karnes et al, 1998; Ogino et al, 2006; Yuan et al, 2009; Colussi et al, 2013).
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Finally, there is an increasing interest in combining molecular variables with previously established models.
The combined effect of bi-allelic loss of FAM46C was not significant, whereas loss alone was, Supplementary Tables 2 and 4. Interactions between molecular variables were tested, Supplementary Table 6.
It is a combination of a genetic algorithm (GA) that optimizes the discrete molecular variables and a gradient-based deterministic algorithm that solves the continuous nonlinear optimization problem of the process at fixed molecular variables as proposed by the GA.
All our polyethylenes are centred on medium density materials but they differ with respect to molecular variables.
A case-cohort study was designed to correlate various histopathologic and molecular variables with distant failure in endometrial cancer by analyzing phenotypic and molecular indices in hysterectomy specimens.
This correlation gave basis that the implied molecular variables can become trackers for the calculation of TBARS inhibitory concentrations in similar systems.
Conclusions: Preoperative evaluation of quantifiable cytokinetic and molecular variables can assist in identifying tumor types that are predisposed toward a more aggressive clinical course.
Thus, large numbers of molecular variables (p) can be measured in a small number of samples (n), presenting what is known as the high-dimension, low-sample-size dilemma (p>>n), which is common in -omics sciences.
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