Sentence examples for molecular tests with from inspiring English sources
Insights into the extent to which culture is falsely negative can be gained using molecular tests with a higher predicted diagnostic sensitivity, although both culture and molecular tests are prone to reduced sensitivity from factors such as inadequate sampling, the intermittent presence or low number of organisms in specimens such as blood, and prior administration of antimicrobial therapy [1].
11 Consciousness of this led to the development of molecular tests with higher sensitivity compared to cytology.
Accurate measurement of DNA using quantitative real-time PCR (Q-PCR) techniques is fundamental to many molecular tests with clinical [ 1], environmental [ 2], and forensic applications [ 3].
Results from detecting BRAFV600E mutations in melanoma with use of molecular tests with IHC methods are highly correlated with results from IHC staining with anti-BRAFV600E (clone VE1), with a sensitivity of 97%–100% and a specificity of 98%100%%.
The molecular test with the new primers improved the sensitivity to 100%.
Clinical studies comparing these two tests and the molecular test with treatment outcome are needed.
Hence, a binary outcome of a molecular test with a predetermined cut-off value can prove advantageous in this regard.
Molecular testing with first-line targeted crizotinib treatment in this population resulted in a gain of 0.011 QALY compared with standard care.
The diagnosis of JHS/EDS-HT still remains unsupported by molecular testing, with the exception of a very few cases purportedly mutated in COL3A1 and TNXB [ 4– 6].
All identified MDR-TB cases should be managed by specialised centres directly upon diagnosis and a second independent molecular test with a different technology should be performed to confirm the rapid diagnosis [ 32– 32].
The higher analytical sensitivity of PCR explains the higher detection rates compared to HC2 in samples with low-grade cytological and no histological abnormalities and may be suggestive of the presence of latent HPV infection requiring a molecular test with higher analytical sensitivity.
