Cheng, L., Lopez-Beltran, A., Massari, F., MacLennan, G. T. & Montironi, R. Molecular testing for BRAF mutations to inform melanoma treatment decisions: a move toward precision medicine.
Discussion of principles of molecular testing for diagnosis of somatic and germline diseases using FISH, classical genotyping, array CGH, next generation sequencing, and other technologies.
These fields don't yet have the genetic knowledge that cancer does Elton estimates that the state of molecular testing for neurodegenerative disease resembles that of cancer five years ago.
This article describes the major points of this new classification and underlines the role of the pathologist in the molecular testing for treatment selection.
(2) Seek molecular testing for known mutations of cystic fibrosis in relevant family members to determine with greater accuracy whether either or both prospective parents are carriers for this recessive disorder.
An important consideration in the molecular testing for HHV-6 is the existence of two distinct virus variants, known as HHV-6A and HHV-6B with a common genome organization, and some 90% nucleotide sequence identity.
We review the literature on (i) the specificity and heterogeneity of ILC biology as documented by various analytical techniques, including the results of molecular testing for risk of recurrence; (ii) the impact of lobular histology on prediction of prognosis and effect of systemic therapies in patients.
Intraoperative pathologic examination in the era of molecular testing for differentiated thyroid cancer.
So the accuracy of clinical molecular testing for genetic instability could be compromised by DNA contamination if undetected, leading to erroneous determinations of genetic instability.
This was a combined cytogenetic and molecular laboratory, offering cytogenetic testing for prenatal, constitutional and cancer cases, array CGH analysis and molecular testing for several constitutional diseases and somatic cancer mutations.
The University of Chicago Genetic Services Laboratories has been offering diagnostic testing for Cornelia de Lange syndrome since 2006, and has developed considerable expertise in molecular testing for this condition.
