Sentence examples for molecular template to from inspiring English sources
Combretastatin A-4 (CA-4) is a well-studied and attractive molecular template to develop new antimitotics.
Through high throughput screening, parallel synthesis, X-ray crystallography, and structure based drug design, we have developed the first non-chiral, non-peptidic, small molecular template to possess moderate potency against renin.
These data show that an antibody raised against an unstable mutant can act as a molecular template to induce aberrant behaviour in a wild-type protein.
Several types of repeats as leucine rich-repeat (LRR) [ 17, 18] tetratricopeptide (TPR), armadillo, HEAT and ankyrin repeats have been used as molecular template to develop large libraries of binding scaffolds [ 18, 19].
DOI: http://dx.doi.org/10.7554/eLife.01630.001 Cells are complex environments: at any one time, thousands of different genes act as molecular templates to produce messenger RNA (mRNA) molecules, which themselves are templates used to produce proteins.
In addition to iron, a DMP molecular template was also introduced to AFeC to create special molecular imprinting affinity for DMP.
Specific examples where this approach has generated either significant modifications of existing molecular frameworks or structurally new molecular templates relative to design starting points (i.e., lead hopping) will be provided.
To estimate the conditional probabilities P (e i |e1, e2,⋯,ei-1), we need training data consisting of a large number of Euler circuits each corresponding to some particular molecular template.
Nebulin is a very large (Mr 600 900 kDa) actin-binding protein that is specific to skeletal muscle, and which is thought to act as a molecular template that regulates the length of sarcomere thin filaments.
This indicates a molecular templating mechanism, similar to that observed in the synthesis of MCM41.
Many studies and reviews on the topic of neurodegenerative diseases with LBs are organized as if "molecular template" for αS and its spread along "structural template" are unequivocally coupled to provide a direct mechanism to explain the progressive clinical and pathological nature of these disorders.
