Sentence examples for molecular targets affected from inspiring English sources

Further studies should elaborate on the distinct pathways and molecular targets affected by naa10 MO.

The molecular targets affected by the SE-triggered NO pathway are unknown.

These phytochemicals exert their anticancer effects through modulation of multiple molecular targets affecting various signaling pathways [ 8, 14, 15].

Among the various molecular targets probably affected by lipid peroxidation during oxidative stress in diabetes, LDL is one of the most important.

Many of these molecular targets are only affected by concentrations of EGCG that are far above the levels achieved by either drinking green tea or consuming moderate doses of green tea extract-based dietary supplements.

Overall, these data have identified yet another system and additional molecular targets that are affected long term by adolescent alcohol exposure and may lead to better understanding of factors that regulate HPA axis maturation during pubertal development.

The identification of the molecular targets that are affected by SIRT1 phosphorylation, especially at sites modified by cell cycle-dependent kinases like Cdk1, will help to elucidate how changes in the level and activity of SIRT1 affect diverse processes such as growth and longevity in organisms ranging from single-celled yeast to mammals.

In this context, we emphasize the urgent need of: i) rapid molecular tests able to provide adequate information to select the most appropriate direct antibiotic treatment [ 30]; ii) novel antimicrobial families against molecular targets not yet affected by resistance mechanisms [ 4]; iii) increasing numbers of cultures to study and monitor clonality and resistance mechanisms of gonococcus [ 4].

Thus, more neuroblastoma-optimized therapy approaches aiming at oncogenic molecular targets, for example, affecting neuroblastoma cell maturation and proliferation, are believed to improve therapeutic efficacy, reduce toxicity and avoid long-term side effects.

The effects of CBD on microglial cells in vitro and in vivo led us to search for the molecular targets that may be affecting cell function and viability.

An appropriate reproducible classifier is thus urgently needed to define good and poor treatment response subgroups and for the evaluation of results obtained from clinical trials in order to validate the potency of new drugs specifically designed to selectively affect molecular targets in the respective subclasses.