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Together, this study revealed CPSF6 as a molecular target with clinical relevance for prognosis and therapy in breast cancer.
Acetylcholinesterase (AChE) is a molecular target with a considerable amount of data related to its sequence and 3-dimensional structure.
In particular, aptamers (non-coding, synthetic, single-stranded DNA or RNA oligonucleotides) are of interest because they can bind a molecular target with high affinity and specificity.
Aptamers are nucleic acids (DNA or RNA) that bind any given molecular target with high affinity and specificity.
This in turn has huge potential advantages since MRI, unlike nuclear imaging techniques, can demonstrate anatomy along with the molecular target, with enormously high spatial resolution.
These data suggest that IL-32γ might be a molecular target with the potential to prevent radiographic progression in AS.
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Moreover, the biomarkers indicating such aggressiveness can represent molecular targets with the future development of small-molecule targeted therapy.
Modern anticancer strategies are designed against specific molecular targets with the goal of sparing normal, non-neoplastic tissues.
Functional overexpression or inhibition studies of these molecular targets with animal models of AD would follow to give more mechanistic insights….
It could also guide future neurological therapeutic interventions based on the identification of the mechanisms of action and molecular targets with the potential to ameliorate any anesthetic-induced neural injury.
Protocols involving molecular targeting with an engineered unlabeled protein derived from an antibody, followed by capture of a small probe molecule that provides a signal, are being developed to a high level of utility.
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