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However, the molecular system underlying TNF-induced angiogenesis is not well understood [ 7].
We analyzed the gene expression changes stimulated by TNF in HUVEC over a time course using microarrays to reveal the molecular system underlying TNF-induced angiogenesis.
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Using a liquid-chromatography mass spectrometry-based "bottom-up" proteomic approach, we analyzed the global proteome profiles of F1 in an attempt to provide insight into the molecular systems underlying the cellular stress response to an acute exposure of chromate.
Importantly, our data demonstrate that a conserved molecular patterning system underlies the great variability of ontogenetic modes and architectures observed in the digestive systems of ecdysozoans.
By associating the spring element with resistance to expansion by the absorbent and the dashpot element with resistance to permeation and by relating the behaviour of the elements to the polymerisation system, underlying molecular factors influencing absorption behaviour could be identified.
However, the molecular system that underlies TNF-induced angiogenesis is largely unknown.
Incorporation of molecular interactions is therefore an important area for further development, where greater fidelity with molecular systems that underlie disease mechanisms can be achieved.
Laminar-specific innervation organizes a wide range of neural circuits throughout the nervous system, and molecular mechanisms underlying laminar organization are likely conserved.
However, molecular mechanisms underlying immune system activation are not completely understood.
Developmental neurobiologists have made great progress in elucidating the molecular mechanisms underlying nervous system development.
The molecular genetics underlying mating system variation, where repeated dioecious – hermaphrodite switches during evolution are recognized, and the molecular evolution of sex-related genes are key questions currently hampered by a lack of genomic information.
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