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Thus, JNK acts as a molecular switch to allow either endurance adaptations when inactive, or growth/hypertrophy adaptations when active.
We also suggest that Id3 acts like a molecular switch to decide the cellular fate for fibroblast transdifferentiation in corneal fibrosis (Supplementary figure S5).
Molecular switch: The tip of a scanning tunneling microscope (shown in silver) probes a cross-shaped molecular switch to turn on and off a neighboring molecule.
Nishimura, Y. et al. Enterovirus 71 binding to PSGL-1 on leukocytes: VP1-145 asts as a molecular switch to control receptor interaction.
Thus the reversible process of phosphorylation/dephosphorylation can be used as a kind of molecular switch to control elastase activity.
Based on these results, we suggest that the RhoA-ROCK-PTEN pathway acts as a molecular switch to control cell proliferation and determine anchorage dependence.
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Feringa, B. L. The art of building small: from molecular switches to molecular motors.
This prompts the molecular switches to crosslink, or bind one to another.
This is highly significant when designing molecular switches to perform logic operations.
Biological networks are highly complex systems, consisting largely of enzymes that act as molecular switches to activate/inhibit downstream targets via post-translational modification.
While such a switch is still years from being used in working devices, the scientists suggest that it does show a potential way to link together such molecular switches to form molecular logic gates for future computers.
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