Sentence examples for molecular switch from from inspiring English sources

DAEs contained thiosemicarbazone (TSC) and methylthiosemicarbazone (MTSC) side-chain groups (Fig. 1b) that were used to extend π-system of photochromic switches [13, 14] and to decouple the molecular switch from the gold electrodes and, thus, to avoid the unintended quenching of the excited state [11, 15].

In an effort to search for key molecules in the signalling network upstream of the identified transcription factors the insulin-like growth factor pathway was identified that indeed may represent a molecular switch from the EGF receptor tyrosine kinase route to the tumour state thereby rendering malignantly transformed cells independent of EGF receptor activity.

We analyzed the mechanism underlying the molecular switch from proliferative to migratory action of androgens.

MDCK cells spontaneously form cysts when cultured in 3D collagen gels and undergo in vitro tubulogenesis when treated with HGF; thus HGF functions as a "molecular switch" from cyst to tubule formation [ 15].

To further examine the mechanism by which cyst formation occurs by means of p21 attenuation, we utilized the growth factor HGF. MDCK cells spontaneously form cysts when cultured in 3D collagen gels and undergo in vitro tubulogenesis when treated with HGF; thus HGF is functions as a molecular "switch" from tubule formation to cyst [ 15].

It has been hypothesized that the molecular switch from sex to apomixis is associated with gene-specific silencing mechanisms associated with chromatin remodeling factors or trans-acting and heterochromatic interfering RNAs involved in both transcriptional and post-transcriptional gene regulation [ 27].

Thus, BubR1 acetylation/deacetylation serves as a molecular switch for the conversion of BubR1 from inhibiting the APC/C complex to becoming its substrate.

This important task is accomplished by the heterotrimeric troponin complex anchored on the thin filament by its tropomyosin-binding subunit cTnT. 1 The inhibitory subunit cTnI acts as a molecular switch moving from actin to the Ca2+-binding subunit cTnC as the intracellular Ca2+ concentration increases.

This FLPe-responsive molecular switch, which differs from those usually applied in recombinase-activatable transgenes, was chosen to minimize reporter gene basal activity in the "off" state and to avoid chromosomal position effects, including transcriptional interference, on reporter gene expression in the "on" state.

KRas is a membrane-bound guanosine triphosphate (GTP /guanosine diphosphate (GDP -binding (GDP -bindinghat serves as a "molecular switch," convertinG signals from the cell membrane to the nucleus.

Such an interaction could either regulate a molecular switch shifting viral RNA from replication to packaging, or otherwise facilitate infectious GBV-B particle assembly.