Sentence examples for molecular surrogate from inspiring English sources

These results drive the design of more effective COEs that will serve as an exact molecular surrogate for outer membrane cytochromes.

To this end, we assessed if detection of global reduction of H3K27me3 by immunohistochemical staining could be used as a molecular surrogate for H3F3A K27mutationsns.

None of the other epidemiological studies report on specific fatty acids and the risk of molecular surrogate end-points for colon or rectal cancer or adenomas [ 35– 435.

The absolute requirement for TRPV1 for NGF-dependent heat hyperalgesia and nociceptor sensitization has led many workers to use increased TRPV1 activity as a molecular surrogate for sensitization.

These results suggest that the phylogenetic analysis based on the VP4 nucleotide sequences is also useful as a molecular surrogate for antigenic HEV serotyping.

DOI: http://dx.doi.org/10.7554/eLife.00070.019 Using FLAG-H2BE as a molecular surrogate for H2BE, we examined the histone variant's localization on genomic DNA.

Finally, studying early placentation may provide targets for development of novel molecular approaches, such as up-regulate or down-regulate genes, the protein products of which could potentially serve as molecular surrogates for diagnosis and treatment of pregnancy complication such as miscarriages, pre-eclampsia, pregnancy induced hypertension and intrauterine growth retardation.

Age-grading methods that delineate chronological age, using accurate molecular surrogates based upon gene expression profiles, will allow quantification of the longevity-reducing effects of vector control tools aimed at the adult, female mosquito.

Instead of having to rely on molecular surrogates with a limited resolution, such an approach would be highly informative both by giving a more accurate picture of ongoing tuberculosis transmission and related epidemiological outcomes such as re-infection and mixed infections, as well as by shedding light on the microevolutionary processes occurring in M. tuberculosis during spread.

The discrepancy between molecular- and surrogate pathology-based clinical subtyping is reasonable because the two methods are based on different genotypic features of the tumor; where hormone receptors and HER-2 are measured individually, BluePrint is designed according to a rational-based method such that it captures the functional underlying biologic pathway regulated by ER, PR, and HER-2 [ 3].

Specific forms of vimentin can be surrogate molecular indicators of the invasive/infiltrative phenotype in tumors.