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The "intrinsic gene set" data generated by Sorlie et al. [2] to classify breast tumors into five molecular subtypes was used to filter cell line data generated by Charafe-Jauffret et al. [13].
The relationship between AD and molecular subtypes was modelled via multinomial logistic regression.
For these reasons, direct PLS modeling of five molecular subtypes was not practical.
Classification of intrinsic molecular subtypes was carried out according to new guidelines [ 14].
Distribution of these molecular subtypes was, however, significantly different between the three age groups (p < 0.001).
Concordance analysis of receptor status and molecular subtypes was performed on CNB and OEB samples.
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Gene expression analysis indicates that the major CRC molecular subtypes are represented.
The 5 molecular subtypes are marked by several clinical characteristics.
Our findings warrant validation in large prospective studies where complete data on molecular subtypes are available.
Molecular subtypes were defined by PAM50 [ 17].
Molecular subtypes were defined by immunohistochemistry (IHC).
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