Sentence examples for molecular subtypes observed from inspiring English sources

Subclass mapping, a method that statistically measures the similarity of predetermined subtypes in independent datasets, was used to test the correspondence of intrinsic molecular subtypes observed in Chinese and Caucasian gene expression data.

Like with tumor-specific markers, variation between histological and molecular subtypes was observed for TfR, Mammaglobin, and CAXII.

In agreement with other studies, a significant association between clinical-pathological features and molecular subtypes was observed [ 3, 6, 8, 31].

No statistically significant difference in metastatic site (visceral vs. other) or in the distribution of immunohistochemistry-defined molecular subtypes was observed according to CTC value.

A similar distribution of the five molecular subtypes was also observed when we used a newer intrinsic subtype classifier, PAM50 [ 23], a 50-gene subtype predictor, with more luminal B tumors grouped into CMTC-2.

The differences in molecular subtypes that we observed among the five geographic regions persisted in the subgroups of patients under and over 50 years, suggesting the existence of a geographic phenomenon more than effect of age itself.

We next investigated the predictive value of the metagenes in the context of the intrinsic molecular subtypes, as we previously observed the prognostic value of the metagenes to segregate most significantly with the basal, HER2-E and LumB subtypes [ 36].

The most frequent change in molecular subtype that we observed after cycle 1 of NAC was from luminal B to luminal A. Korde and colleagues reported similar findings [ 31].

We observed that molecular subtypes were independently associated with age by multivariate analysis.

This increase in 'mutational load' was also observed within molecular subtypes of diffuse glioma and is listed in Table  5.

In contrast, a significant association was observed between GBMs molecular subtypes and response rates.