Sentence examples for molecular subtypes including from inspiring English sources

Classification of prostate cancer into distinct molecular subtypes, including mutually exclusive ETS-gene-fusion-positive and SPINK1-overexpressing, CHD1-loss cancers, could allow stratification of patients for different management strategies.

TOX3 was expressed across multiple molecular subtypes, including luminal, molecular apocrine, and normal-like.

We also extended the analysis of Toca-1 levels to the major molecular subtypes, including luminal, HER2 and TNBC.

The expression level and cellular localization of CXCR4 in human breast tumours have also been analyzed in view of its molecular subtypes, including triple-negative breast cancers (TNBC), luminal subtypes, and HER2-positive breast cancers, via IHC.

There was no significant difference in the expression levels of Bcl-2 transcripts in the four breast cancer molecular subtypes, including up-regulation, down-regulation and no change (P = 0.282).

Hierarchical clustering analysis of this data set using the ~1,900 intrinsic gene list of Parker et al. [ 9] identified the major intrinsic molecular subtypes, including the claudin-low subtype.

These molecular subtypes include: basal cell-like, Her-2/neu, luminal A, and luminal B.

The established prognostic factors molecular subtype, (including hormone receptor status, histological grade and HER2 receptor status), tumor size and nodal status remain independent prognostic factors on disease outcome in young breast cancer patients.

Furthermore, miRNAs are differentially expressed between molecular breast cancer subtypes, including luminal A, luminal B, basal-like and Her2+ (Blenkiron et al, 2007).

Breast cancer is a highly heterogenous disease at the morphologic and molecular level, with at least four main molecular subtypes described, including luminal (divided into luminal A and B), HER2 over-expressing, and basal-like [ 1– 3].

The Mouse Tumor Biology Database (MTB; http://tumor.informatics.jax.org) is designed to facilitate use of mouse models of human cancer by providing detailed histopathologic and molecular information on lymphoma subtypes, including expertly annotated, on line, whole slide scans, and providing a repository for storing information on and querying these data for specific lymphoma models.