Sentence examples for molecular subtypes determined from inspiring English sources

Subsequently, investigators have demonstrated that constructed molecular subtypes determined using ER, PR and HER2 status corresponds with these molecular subtypes thus allowing clinicians to apply this concept to patient care and decision making [ 30].

There was no obvious relationship between this clustering and the breast cancer molecular subtype, determined by the PAM50 centroids.

The following section describes human ILC cell lines and their molecular properties.> -wrap-foot> All information compiled from the literature; molecular subtype determined by microarray expression profiling in different studies.

Molecular subtypes were determined using PAM50 centroids [ 23].

Molecular subtypes were determined using immunohistochemical surrogate markers, which were stained during routine surgical pathology practice.

Due to missing values for hormone receptor and/or HER2 status, molecular subtypes could be determined for only 3670 of the 3754 randomized patients (Table  1).

The aim of this study was to investigate the clinicopathological significance of these molecular subtypes and to determine whether patients with BAP1-mutant and PBRM1-mutant tumours had different overall survival.

We determined molecular subtypes and the scores of relative risk of distant recurrence.

For validation, we used our classifier genes with centroid analysis to determine molecular subtypes of breast cancer samples in three independent datasets [ 10, 19, 20].

To determine molecular subtypes, RNA extracted from 22 specimens of fresh frozen human glioma using TRIzol and from the corresponding GC lines in the same manner as described above, was used in a custom-made assay by NanoString Technology.

To determine molecular subtypes we characterized over 200 tumor specimens obtained from Egypt by performing ER, PR, Her2, CK5/6, EGFR and Ki67 immunohistochemistry. Our study demonstrated that the Luminal A subtype, associated with favorable prognosis, was found in nearly 45% of cases examined.