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Gene expression analysis indicates that the major CRC molecular subtypes are represented.
The 5 molecular subtypes are marked by several clinical characteristics.
Our findings warrant validation in large prospective studies where complete data on molecular subtypes are available.
Further molecular subtypes are now known to exist within the 4 molecular types (15 ).
Molecular subtypes are largely and consistently recognized as predictors of recurrence and death [ 10- 12].
In fact, our results indicated that more aggressive molecular subtypes are more prevalent in the North.
Similar(25)
Molecular subtypes were defined by PAM50 [ 17].
Molecular subtypes were defined by immunohistochemistry (IHC).
Molecular subtypes were also evaluated as described below.
Research on the epidemiology of molecular subtypes is challenging.
Differences among the other three molecular subtypes were small.
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