Sentence examples for molecular subtypes and from inspiring English sources

Only large scale clinical testing will help us with understanding these molecular subtypes and designing therapies for patients with DLBCL.

The aim of this study was to investigate the clinicopathological significance of these molecular subtypes and to determine whether patients with BAP1-mutant and PBRM1-mutant tumours had different overall survival.

Multifocal/multicentric invasive ductal carcinomas usually have a single phenotype in terms of hormone receptors, human epidermal growth factor receptor 2, and molecular subtypes; and thus, immunohistochemical analyses of the index tumor may be sufficient in routine practice.

Therefore, rather than treating melanoma as a single disease, it makes sense to stratify tumors into molecular subtypes and treat each with the most appropriate therapies.

Low and high-risk tumors were enriched for favorable and unfavorable molecular subtypes and pathways, previously defined in the public 2nd validation set.

We validated and confirmed the molecular subtypes and their associated clinicopathological features with expression data from a second independent series of 46 medulloblastomas.

Microarray-based gene expression profiling has been used extensively to characterize the transcriptome of breast cancer, resulting in the identification of new molecular subtypes and markers or signatures of potential therapeutic and prognostic importance [1] [12].

The model consists of a set of actionable molecular subtypes and proposed practice guidelines for treating each subtype: which therapies (approved or experimental) should be considered and which are contraindicated (see Tables 1 and 2).

We also assessed the relationship between immune responses and molecular subtypes and their prognostic potential.

We then conducted statistical analysis between the molecular subtypes and various clinical parameters (Table 2).

We determined molecular subtypes and the scores of relative risk of distant recurrence.