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CNB was accurate in evaluating ER, PR, HER2, and molecular subtype status.
Our concordance analysis demonstrated that CNB was accurate in determining molecular subtype status compared with SRS.
Our study has demonstrated that CNB is accurate in evaluating ER, PR, HER2, and molecular subtype status in breast cancer.
Our previous study showed that CNB had a high concordance rate in evaluating molecular subtype status compared with those in surgically removal samples (SRS) [ 4].
Our present study demonstrated that CNB was accurate in evaluating breast cancer receptor and molecular subtype status compared with subsequent SRS.
Until recently, most studies using IHC to assign molecular subtype status to breast cancer have not used Ki67 to discriminate between Luminal A and B and rather only used Her2 status [ 7].
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The table reports on intrinsic molecular subtype, receptor status, histological classification and metastatic potential.
Associations between RRBP1 expression and patients' clinicopathological features, including age, tumor size, lymph node metastasis (LNM), TNM stage, histological grade, molecular subtype, and status of ER, PR, Her-2, Ki67 and P53 were assessed using the χ-test.
Comparisons of the age of patients between different geographic regions, molecular subtypes, ER/PR status, and HER2 status were performed using the Kruskal-Wallis test.
Importantly, the first three components are significantly associated with molecular subtypes, ER status, histological grade and lymph node status.
Breast clinical variables included molecular subtype, lymph node status, estrogen receptor status, size, age, grade, and recurrence-free survival.
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