Sentence examples for molecular subtype designations from inspiring English sources

Conversely, re-analysis of the TCGA GBM data with Phillips molecular subtype designations confirmed a slightly more favourable prognosis of the Phillips proneural GBM (median overall survival 1.2 y) relative to Phillips mesenchymal/proliferative GBM subtypes (1.0 and 0.6 y, respectively, P=0.03).

Molecular subtype assignment according to the subtype clustering method [ 17].

Molecular subtype annotation was performed by means of six molecular subtype predictors (MSPs) and lead to robust molecular subtype predictor classification (RMSPC), which only includes patients with concordant molecular subtype assignment for the 6 MSPs (1).

The biological conformity observed within each consensus molecular subtype (CMS) holds promise for the design of subtype-specific treatment regimens.

In addition, a metagene score-based approach for subtype designation assessing four mesenchymal and two proneural genes using a microfluidics-based quantitative PCR assay was performed to identify the mesenchymal molecular subtype of GBM 276 as previously described.

Our findings did not support an association between the uptake of either radiopharmaceutical and molecular subtype.

Molecular characterization and novel therapeutic targets of each molecular subtype have been identified.

Molecular classification of a patient's disease should improve choices of therapy at diagnosis, given a particular molecular subtype, and lead to development of new therapies for subtypes with a poor prognosis.

Our findings did not support an association between the uptake of either radiopharmaceutical and tumor molecular subtype.

Molecular subtype of malignant lesions was characterized as luminal (ER+ and HER2−), HER2-enriched (HER2+/ER−/PR−), or triple negative (ER−/PR−/HER2−).

Mazurowski et al [38] found that the Luminal B molecular subtype is associated with enhancement dynamics on MRI.