Sentence examples for molecular subtype compared from inspiring English sources
Sixty-three oft of 373 (17 %) tumors had a discordant molecular subtype compared to the surrogate pathology-based IHC/FISH subtype.
In total, 63 out of 373 (17 %) patients had a different molecular subtype compared to the surrogate-based pathologically determined subtype.
Given that the prognostic impact of Tregs appears to differ based on ER status, histological grade, and molecular subtype, comparing the biology of Tregs in distinct tumour phenotypes may provide valuable insights into both Treg biology and breast cancer immunology.
Pre-menopause state tended to be increased for patients with tumors of Luminal B (38.89%) and TN (33.33) molecular subtypes compared to those with tumors of Luminal A (22.73%) and HER2 (26.92%) subtypes (Table 1).
We explored the added predictive value of molecular subtyping compared with Ki67 status alone by testing the interaction between the molecular subtype factor and the treatment arm in a Cox model adjusted for the pre-planned histo-clinical variables and Ki67 by treatment interaction.
This classifier also showed improvement in the degree of statistical significance between all molecular subtypes compared with the previously reported five biomarker panel, which was observed for LRR P=0.0004 (previously 0.012), DMFS P<0.0001 (previously 0.0035) and BCSS P=0.0001 (previously 0.048) but not for IBTR (P=0.074, previously 0.346, Figure 2).
Our concordance analysis demonstrated that CNB was accurate in determining molecular subtype status compared with SRS.
Our present study demonstrated that CNB was accurate in evaluating breast cancer receptor and molecular subtype status compared with subsequent SRS.
Our previous study showed that CNB had a high concordance rate in evaluating molecular subtype status compared with those in surgically removal samples (SRS) [ 4].
Rates of pCR were calculated for each BluePrint/MammaPrint molecular subtype and compared with pCR rates for subgroups classified by IHC/FISH.
The classifications of primary breast cancer tumours and corresponding lymph node metastases by molecular subtypes were compared using the exact McNemar-Bowker test of symmetry.
