Sentence examples for molecular subtype and from inspiring English sources
Early recommendations on management were made by Bioulac-Sage et al. based on the clinical features, gender, molecular subtype and imaging features [39].
Molecular classification of a patient's disease should improve choices of therapy at diagnosis, given a particular molecular subtype, and lead to development of new therapies for subtypes with a poor prognosis.
Targeted next-generation sequencing has the potential to stratify a tumor by molecular subtype and aid the development of a biomarker profile for prognostic risk stratification and theranostic potential.
Messina allows the detection of genes with profiles typical of markers of molecular subtype, and complements existing methods to assist the identification of such markers.
Experiments with a larger and more diverse cancer cell line panel may eventually reveal additional correlations between cancer cell tissue of origin or molecular subtype and growth response in co-culture.
In addition, we found that nucleic acids prepared from CTCs captured using the CellSearch® RUO Profile kit were also amenable to biomarker assays including a qRT-PCR gene expression assay for breast cancer molecular subtype, and a PCR-based assay for KRAS mutations.
Only large scale clinical testing will help us with understanding these molecular subtypes and designing therapies for patients with DLBCL.
Low and high-risk tumors were enriched for favorable and unfavorable molecular subtypes and pathways, previously defined in the public 2nd validation set.
We validated and confirmed the molecular subtypes and their associated clinicopathological features with expression data from a second independent series of 46 medulloblastomas.
Therefore, rather than treating melanoma as a single disease, it makes sense to stratify tumors into molecular subtypes and treat each with the most appropriate therapies.
There were no proportional differences between molecular subtypes and tumour immune subtypes (P=0.6) (Table 3A).
