Sentence examples for molecular subgroups we from inspiring English sources

By analyzing their patterns of expression across MB molecular subgroups, we showed that NOTCH ligand JAG1 is broadly over-expressed in MBs, and homogeneously distributed across subgroups.

To obtain additional evidence that KRAS genomic amplifications represent a distinct gastric cancer molecular subgroup, we performed a Kaplan Meier survival analysis comparing outcomes of patients with KRAS-amplified samples versus patients with tumours lacking RTK or KRAS amplification.

Our results reveal relationships between cancers in different tissues, show the existence of new molecular subgroups across tissues and we found a signature predictive of clinical outcome.

To analyze the relationship between the immune microenvironment and molecular subgroups of various cancers, we developed a method to identify and measure the expression of genes specific to the main immune and stromal cell populations.

We have investigated clinical and molecular characteristics of the ETP-ALL subgroup in adult T-ALL.

Similarly, we identified distinct molecular subgroups of BRAF-mutant tumors, and multidimensional analyses highlighted a potential involvement of oncomiRs in less-differentiated subgroups.

Thus, we determined 12 molecular subgroups that were characterized by a relative over-expression or under-expression of distinct combinations of genes.

We also evaluated the molecular subgroups.

To assess the statistical relevance of the molecular subgroups as defined by the hierarchical clustering, we performed a Chi2 analysis of the data (see Methods).

We assessed the possibility of molecular subgroups within the combined cohort defined by copy number using hierarchical clustering (Figure S1).

We further characterized these four molecular subgroups.