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However, from molecular studies it was not clear whether non-Mendelian rDNA inheritance was caused by a decrease in copy number (elimination) or unit replacement (e.g. via homogenisation mechanisms).
Despite the great development in molecular studies, it is estimated that mutations in the SCN5A gene cause only about 18 30% of BS cases [ 17].
Based on recent clinicopathological and molecular studies, it has been proposed that surface epithelial tumours could be divided into two broad categories, type I and type II tumours.
According to epidemiological and molecular studies, it is well-established that human papillomavirus (HPV) infection is the main etiological factor for cervical cancer and premalignant lesions of the cervix [ 4, 5].
Combined with previous cytological and molecular studies, it can be concluded that the Psathyrostachys species served as the Ns genome donor during the polyploid speciation of the Leymus species.
If this finding is validated in subsequent genetic and molecular studies, it would suggest that TDP-43 plays a role in the modulation of synaptic homeostasis via the dpp /BMP signaling cascade.
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The fungus was later shuffled to the genera Volvaria and Volvariella before molecular studies placed it in Volvopluteus, a genus newly described in 2011.
After performing molecular docking studies, it was found that compounds 13a and 13d had potential to inhibit pteridine reductase 1 enzyme.
In the molecular modeling studies, it is revealed that most of the antidepressant molecules showed good binding affinity towards MAO-A than MAO-B that is an effective target for the treatment of depression.
Based on molecular dynamics studies it has been hypothesized that dasatinib can bind to both the active DFG- in and inactive DFG- out conformations of Abl [38], [41].
From molecular dynamics studies, it can be inferred that the truncated sn-2 fatty acid folds back to the aqueous phase (carboxylic-phospholipids) or the lipid water interface (aldehydo-phospholipids) [9].
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