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The origin of population and quantitative genetics was built on the knowledge that Mendelian factors underpin continuous variation and gradual evolution, even though molecular, statistical, and computational tools enabling mapping experiments only became available more than half a century later.
To elucidate a detailed picture of the genetic architecture of complex traits, various molecular, statistical, and computational tools have been developed and used in the mapping and identification of specific genes underlying the traits [1] [8].
MH took part in the study design, carried out molecular, statistical and population genetic analyses and drafted the manuscript.
This article reviews recent advances in 'microbiome studies': molecular, statistical and graphical techniques to explore and quantify how microbial organisms affect our environments and ourselves given recent increases in sequencing technology.
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HA took part in the study design and molecular and statistical analyses, contributed photographs and tissue samples from Venezuela, and helped to draft the manuscript.
LB and LK conducted field collection, RTP performed molecular and statistical analysis and drafted manuscript, KJ participated in drafting the manuscript.
DC conceived the study, performed the molecular and statistical analyses and drafted the manuscript.
MB conceived of the study, carried out the molecular and statistical analyses and drafted the manuscript.
ST developed the cDNA libraries, produced the ESTs, developed and screened the DNA markers, performed molecular and statistical genetic analyses, and assisted with drafting the manuscript.
AM generated sequence data and performed molecular and statistical analysis.
SDP performed the molecular biology techniques, statistical and bioinformatic analyses.
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